Article
HLA-G polymorphisms in women with squamous intraepithelial lesions harboring human papillomavirus.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2009
Simões Renata T, Gonçalves Maria Alice G, Castelli Erick C, Júnior Celso M, Bettini Jussara S R, Discorde Magali L, Duarte Geraldo, Quintana Silvana M, Simões Aguinaldo L, Moreau Philippe, Carosella Edgardo D, Soares Edson G, Donadi Eduardo A
Abstract excerpt
Human papillomavirus (HPV) infection is etiologically associated with low- (LSIL) and high-grade squamous intraepithelial lesions (HSIL) and with cervical cancer. The progression or regression of the lesions may depend, among other factors, on the host heritable immune response. Because human leukocyte antigen (HLA)-G molecules are involved in the modulation of innate and adaptive immune responses, and because no...
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