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Article

Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2).

Acta crystallographica. Section F, Structural biology and crystallization communications - 1 May 2009

Wilson Randall C, Hughes Ronny C, Flatt Justin W, Meehan Edward J, Ng Joseph D, Twigg Pamela D

Abstract excerpt

The ubiquitin-conjugating enzyme E2-25K has been identified as a huntingtin (the key protein in Huntington's disease) interacting protein and has been shown to play a role in mediating the toxicity of Abeta, the principal protein involved in Alzheimer's disease pathogenesis. E2-25K is a dual-doma...

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Identifiers

PMID: 19407372
DOI: 10.1107/S1744309109011117
PMCID: PMC2675580

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UBC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19407372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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