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Article

Binding Surface Mapping of Intra- and Interdomain Interactions among hHR23B, Ubiquitin, and Polyubiquitin Binding Site 2 of S5a

1 Sept 2003

Abstract excerpt

hHR23B is the human homologue of the yeast protein RAD23 and is known to participate in DNA repair by stabilizing xeroderma pigmentosum group C protein. However, hHR23B and RAD23 also have many important functions related to general proteolysis. hHR23B consists of N-terminal ubiquitin-like (UbL), ubiquitin association 1 (UBA1), xeroderma pigmentosum group C binding, and UBA2 domains. The UBA domains interact with...

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PMID: 12832454
DOI: 10.1074/jbc.m304628200

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