Article
Association of GSTM1T1 genes with COPD and prostate cancer in north Indian population.
Molecular biology reports - 1 Mar 2011
Thakur Hitender, Gupta Lipsy, Sobti Ranbir C, Janmeja Ashok K, Seth Amlesh, Singh Sharwan K
Abstract excerpt
The glutathione S-transferase (GST) family of enzymes is known to play a pivotal role in phase II of biotransformation of xenobiotics, environmental carcinogens and pharmacological drugs. The objective of the present study was to investigate the role of GSTM1 and GSTT1 null genotypes as risk factors for chronic obstructive pulmonary disease (COPD) and prostate cancer. The subjects appraised were 200 COPD cases,...
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