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Article

Rapid molecular characterization of Clostridium difficile and assessment of populations of C. difficile in stool specimens.

Journal of clinical microbiology - 1 Jul 2009

Wroblewski Danielle, Hannett George E, Bopp Dianna J, Dumyati Ghinwa K, Halse Tanya A, Dumas Nellie B, Musser Kimberlee A

Abstract excerpt

Our laboratory has developed testing methods that use real-time PCR and pyrosequencing analysis to enable the rapid identification of potential hypervirulent Clostridium difficile strains. We describe a real-time PCR assay that detects four C. difficile genes encoding toxins A (tcdA) and B (tcdB) and the binary toxin genes (cdtA and cdtB), as well as a pyrosequencing assay that detects common deletions in the...

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Identifiers

PMID: 19403775
DOI: 10.1128/JCM.02498-08
PMCID: PMC2708487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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