Article
RNA (E6 and E7) assays versus DNA (E6 and E7) assays for risk evaluation for women infected with human papillomavirus.
Journal of clinical microbiology - 1 Jul 2009
Cattani Paola, Siddu Alessia, D'Onghia Sara, Marchetti Simona, Santangelo Rosaria, Vellone Valerio G, Zannoni Gian Franco, Fadda Giovanni
Abstract excerpt
In the majority of cases, high-risk human papillomavirus (HR HPV) infections regress spontaneously, with only a small percentage progressing to high-grade lesions. Current screening methods are based on DNA detection. An alternative would be to monitor expression of the E6 and E7 viral oncogenes...
Topics
- Adult
- DNA, Viral
- Female
- Genotype
- Humans
- Middle Aged
- Nucleic Acid Hybridization
- Oncogene Proteins, Viral
- Papillomaviridae
- Papillomavirus Infections
- Polymerase Chain Reaction
- RNA, Messenger
- RNA, Viral
- Reverse Transcriptase Polymerase Chain Reaction