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Clinical Performance of Human Papillomavirus E6 and E7 mRNA Testing for High-Grade Lesions of the Cervix

15 Oct 2009

Abstract excerpt

Infection with high-risk (HR) human papillomavirus (HPV) is the major cause of cervical cancer. However, relatively few infections progress to malignant disease. Progression to malignancy requires the overexpression of the E6 and E7 genes in the integrated HPV genome. It follows that the E6 and E7 transcripts could be useful markers of disease progression. The study presented here tests this possibility, using...

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PMID: 19828739
DOI: 10.1128/jcm.01275-09

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Clinical Performance of Human Papillomavirus E6 and E7 mRNA Testing for High-Grade Lesions of the CervixPMID 19828739Read ↗

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Comparison of oncogenic HPV type-specific viral DNA load and E6/E7 mRNA detection in cervical samples: results from a multicenter study.Semantic proximity Read ↗

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