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Article

How selection affects phenotypic fluctuation.

Molecular systems biology - 1 Jan 2009

Ito Yoichiro, Toyota Hitoshi, Kaneko Kunihiko, Yomo Tetsuya

Abstract excerpt

The large degree of phenotypic fluctuation among isogenic cells highlighted by recent studies on stochastic gene expression confers fitness on some individuals through a 'bet-hedging' strategy, when faced with different selective environments. Under a single selective environment, the fluctuation may be suppressed through evolution, as it prevents maintenance of individuals around the fittest state and/or...

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Identifiers

PMID: 19401676
DOI: 10.1038/msb.2009.23
PMCID: PMC2683726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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