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Article

Surfome Analysis as a Fast Track to Vaccine Discovery

28 Apr 2009

Abstract excerpt

Safe recombinant vaccines, based on a small number of antigenic proteins, are emerging as the most attractive, cost-effective solution against infectious diseases. In the present work, we confirmed previous data from our laboratory showing that whole viable bacterial cell treatment with proteases followed by the identification of released peptides by mass spectrometry is the method of choice for the rapid and...

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PMID: 19401597
DOI: 10.1074/mcp.m800486-mcp200

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