Article
A deeper mining on the protein composition of VA-MENGOC-BC®: An OMV-based vaccine againstN. meningitidisserogroup B and C
30 Oct 2017
Abstract excerpt
The protein composition of an Outer Membrane Vesicle (OMV) preparation that constitutes the active pharmaceutical ingredient of VA-MENGOC-BC®, an effective vaccine against Neisseria meningitidis serogroups B, and C is presented. This preparation has a high lipid content and five abundant membrane proteins (FetA, PorA, PorB, RmpM, and Opc), constituting approximately 70% of the total protein mass. The protein...
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