Article
HLA-B*51 and Behçet Disease.
Ocular immunology and inflammation - 1 Feb 2012
Gul Ahmet, Ohno Shigeaki
Abstract excerpt
Behçet disease (BD) is a multisystem inflammatory disorder of unknown etiology. BD has a multifactorial pathogenesis, and genetics plays a critical role in the development of the disease. Association of HLA-B5/B*51 has been recognized as the strongest genetic susceptibility factor for BD discovered so far. Pathogenic role of HLA-B*51 in BD has yet to be clarified, and available data suggest that there is possibly...
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