The complexity of cellular dedifferentiation: implications for regenerative medicine.

doi:10.1016/j.tibtech.2009.02.007

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Article

The complexity of cellular dedifferentiation: implications for regenerative medicine.

Trends in biotechnology - 1 Jun 2009

Grafi Gideon

Abstract excerpt

Cellular dedifferentiation underlies topical issues in biology, such as regeneration and somatic cell nuclear transfer (SCNT), and signifies the withdrawal of cells from a given differentiated state into a 'stem cell'-like state that confers pluripotency. Recently, there has been growing interest in exploiting the dedifferentiation process to obtain autologous stem cell lineages for use in regenerative medicine....

Topics

Animals
Cell Dedifferentiation
Genetic Variation
Humans
Nuclear Transfer Techniques
Plant Cells
Pluripotent Stem Cells
Regenerative Medicine
Stress, Physiological

Source

Open in PubMed

Identifiers

PMID: 19395104
DOI: 10.1016/j.tibtech.2009.02.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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