Article
The complexity of cellular dedifferentiation: implications for regenerative medicine.
Trends in biotechnology - 1 Jun 2009
Grafi Gideon
Abstract excerpt
Cellular dedifferentiation underlies topical issues in biology, such as regeneration and somatic cell nuclear transfer (SCNT), and signifies the withdrawal of cells from a given differentiated state into a 'stem cell'-like state that confers pluripotency. Recently, there has been growing interest in exploiting the dedifferentiation process to obtain autologous stem cell lineages for use in regenerative medicine....
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