Article
Comparative linkage analysis and visualization of high-density oligonucleotide SNP array data.
BMC genetics - 15 Feb 2005
Leykin Igor, Hao Ke, Cheng Junsheng, Meyer Nicole, Pollak Martin R, Smith Richard J H, Wong Wing Hung, Rosenow Carsten, Li Cheng
Abstract excerpt
BACKGROUND: The identification of disease-associated genes using single nucleotide polymorphisms (SNPs) has been increasingly reported. In particular, the Affymetrix Mapping 10 K SNP microarray platform uses one PCR primer to amplify the DNA samples and determine the genotype of more than 10,000 SNPs in the human genome. This provides the opportunity for large scale, rapid and cost-effective genotyping assays for...
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