Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Factors Influencing the Phenotypic Expression of Hypertrophic Cardiomyopathy in Genetic Carriers.

Revista espanola de cardiologia (English ed.) - 1 Mar 2018

Pérez-Sánchez Inmaculada, Romero-Puche Antonio José, García-Molina Sáez Esperanza, Sabater-Molina María, López-Ayala José María, Muñoz-Esparza Carmen, López-Cuenca David, de la Morena Gonzalo, Castro-García Francisco José, Gimeno-Blanes Juan Ramón

Abstract excerpt

INTRODUCTION AND OBJECTIVES: Hypertrophic cardiomyopathy (HCM) is a disorder with variable expression. It is mainly caused by mutations in sarcomeric genes but the phenotype could be modulated by other factors. The aim of this study was to determine whether factors such as sex, systemic hypertension, or physical activity are modifiers of disease severity and to establish their role in age-related penetrance of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy, Hypertrophic
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Heterozygote

Share to Pedigree

Share to Penetrance

Share to Risk Factors

Source

Identifiers

PMID: 28687478
DOI: 10.1016/j.rec.2017.06.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Factors Influencing the Phenotypic Expression of Hypertrophic Cardiomyopathy in Genetic Carriers.PMID 28687478Read ↗

Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy.Semantic proximity Read ↗

Familial hypertrophic cardiomiopathy: molecular basis and genotype-phenotype correlations.Semantic proximity Read ↗

Manifest disease, risk factors for sudden cardiac death, and cardiac events in a large nationwide cohort of predictively tested hypertrophic cardiomyopathy mutation carriers: determining the best cardiological screening strategy.Semantic proximity Read ↗

Genotype-negative hypertrophic cardiomyopathy: Exploring the role of cardiovascular risk factors in disease expression.Semantic proximity Read ↗

Impact of polymorphisms in the renin-angiotensin-aldosterone system on hypertrophic cardiomyopathy.Semantic proximity Read ↗

Sex-Specific Clinical and Genetic Factors Associated with Adverse Outcomes in Hypertrophic CardiomyopathySemantic proximity Read ↗

Disease penetrance and risk stratification for sudden cardiac death in asymptomatic hypertrophic cardiomyopathy mutation carriers.Semantic proximity Read ↗

Association of duration and intensity of exercise with phenotypic expression in hypertrophic cardiomyopathy.Semantic proximity Read ↗

Modifier genes for hypertrophic cardiomyopathy.Semantic proximity Read ↗

Hypertensive cardiac hypertrophy--is genetic variance the missing link?Semantic proximity Read ↗

Penetrance of familial hypertrophic cardiomyopathy.Semantic proximity Read ↗

Role of candidate modifier genes on the phenotypic expression of hypertrophy in patients with hypertrophic cardiomyopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.