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Article

Target Gene Specificity of USF-1 Is Directed via p38-mediated Phosphorylation-dependent Acetylation

24 Apr 2009

Abstract excerpt

How transcription factors interpret the output from signal transduction pathways to drive distinct programs of gene expression is a key issue that underpins development and disease. The ubiquitously expressed basic-helix-loop-helix leucine zipper upstream stimulating factor-1 binds E-box regulatory elements (CANNTG) to regulate a wide number of gene networks. In particular, USF-1 is a key component of the tanning...

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PMID: 19389701
DOI: 10.1074/jbc.m808605200

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