Article
VNTR typing studies of Mycobacterium leprae in China: assessment of methods and stability of markers during treatment.
Leprosy review - 1 Sept 2009
Xing Yan, Liu Jian, Sakamuri Rama Murthy, Wang Zheng, Wen Yan, Vissa Varalakshmi, Weng Xiaoman
Abstract excerpt
OBJECTIVE: To evaluate the reliability and feasibility of two methods of multilocus variable number of tandem repeat analysis (MLVA) for strain typing of M. leprae, and to study whether short tandem repeat loci are stable and suitable for epidemiological study of leprosy. METHODS: Total DNA was extracted from skin biopsies of 20 new multibacillary (MB) patients from China diagnosed in 2006. To determine the copy...
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