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Article

Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia.

Development (Cambridge, England) - 1 Jun 2009

Schwarz Quenten, Maden Charlotte H, Davidson Kathryn, Ruhrberg Christiana

Abstract excerpt

The peripheral nervous system (PNS) of higher vertebrates is segmented to align the spinal nerve roots with the vertebrae. This co-patterning is set up during embryogenesis, when vertebrae develop from the sclerotome layer of the metameric somites, and PNS neurons and glia differentiate from neural crest cells (NCCs) that preferentially migrate into the anterior sclerotome halves. Previous analyses of mice...

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Source

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Identifiers

PMID: 19386662
DOI: 10.1242/dev.034322
PMCID: PMC2680105

Genes

NRP1
NRP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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