Article
Sorting of striatal and cortical interneurons regulated by semaphorin-neuropilin interactions.
Science (New York, N.Y.) - 3 Aug 2001
Marín O, Yaron A, Bagri A, Tessier-Lavigne M, Rubenstein J L
Abstract excerpt
Most striatal and cortical interneurons arise from the basal telencephalon, later segregating to their respective targets. Here, we show that migrating cortical interneurons avoid entering the striatum because of a chemorepulsive signal composed at least in part of semaphorin 3A and semaphorin 3F. Migrating interneurons expressing neuropilins, receptors for semaphorins, are directed to the cortex; those lacking...
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