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Article

[Conditional lethal mutations shift the genome from stability to instability].

Genetika - 1 Mar 2009

Chadov B F, Chadova E V, Khotskina E A, Fedorova N B

Abstract excerpt

The phenomenology of genomic destabilization is described in Drosophila melanogaster mutants containing radiation-induced conditional dominant lethals in the X chromosome and in autosome 2. Destabilization manifests itself as (1) the loss or decrease of lethality of previously lethal mutations; (2) the loss of expression of visible dominant mutations in an opposite homolog; (3) chromosomal instability resulting...

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PMID: 19382682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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