[Transgenerational transmission of radiation-induced genomic instability and predisposition to carcinogenesis].

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Article

[Transgenerational transmission of radiation-induced genomic instability and predisposition to carcinogenesis].

Voprosy onkologii - 1 Jan 2008

Vorobtsova I E

Abstract excerpt

The paper deals with a history of radiobiological investigations carried out at the Center since 1925 which have contributed to the present-day conception on the influence of damaged DNA on stochastic (carcinogenesis) and non-stochastic (accelerated aging) late radiation pathology in exposed biological objects. A phenomenological and pathogenetic similarity of somatic (in irradiated organisms) and genetic (in...

Topics

Adolescent
Adult
Aged
Child
DNA Damage
Female
Genetic Predisposition to Disease
Genomic Instability
Humans
Male
Middle Aged
Neoplasms
Parents
Radiation Injuries
Radiation, Ionizing
Skin Neoplasms

Source

Open in PubMed

Identifiers

PMID: 18942406

Provenance

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