Article
Papillomavirus DNA complementation in vivo.
Virus research - 1 Sept 2009
Hu Jiafen, Cladel Nancy M, Budgeon Lynn, Balogh Karla K, Christensen Neil D
Abstract excerpt
Recent phylogenic studies indicate that DNA recombination could have occurred in ancient papillomavirus types. However, no experimental data are available to demonstrate this event because of the lack of human papillomavirus infection models. We have used the cottontail rabbit papillomavirus (CRPV)/rabbit model to study pathogenesis and immunogenicity of different mutant genomes in vivo. Although the domestic...
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