Article
Impact of genetic changes to the CRPV genome and their application to the study of pathogenesis in vivo.
Virology - 20 Feb 2007
Hu Jiafen, Cladel Nancy M, Balogh Karla, Budgeon Lynn, Christensen Neil D
Abstract excerpt
The cottontail rabbit papillomavirus (CRPV)/rabbit model has been used to study oncogenicity and immunogenicity of different antigens from the papillomavirus genome and has therefore served as a preclinical model for the development of preventive and therapeutic vaccines against papillomavirus infections. One unique property of the CRPV model is that infection can be initiated using viral DNA. This property...
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