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Article

Differential induction of tumor necrosis factor by bacteria expressing rough and smooth lipopolysaccharide phenotypes.

Infection and immunity - 1 Dec 1991

Kelly N M, Young L, Cross A S

Abstract excerpt

The lipid A portion of the lipopolysaccharide (LPS) molecule of gram-negative bacteria has the ability to turn on the production of tumor necrosis factor (TNF) in macrophage cells. The question addressed in this paper was whether the presence of the polysaccharide moiety on the LPS molecule had any bearing on this ability. The question was asked (i) by using isolated LPS from a series of Salmonella mutants having...

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Identifiers

PMID: 1937808
DOI: 10.1128/iai.59.12.4491-4496.1991
PMCID: PMC259068

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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