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Article

Endometrial claudin-4 and leukemia inhibitory factor are associated with assisted reproduction outcome

19 Apr 2009

Abstract excerpt

BACKGROUND: Claudin-4 (CLDN4) is one of several proteins that act as molecular mediators of embryo implantation. Recently, we examined immunolabeling of leukemia inhibitory factor (LIF) in the endometrial tissue of 52 IVF patients, and found that LIF staining intensity was strongly correlated with successful pregnancy initiation. In the same set of patients, we have now examined endometrial CLDN4 expression, to...

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PMID: 19374770
DOI: 10.1186/1477-7827-7-30

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