Article
Azithromycin maintains airway epithelial integrity during Pseudomonas aeruginosa infection.
American journal of respiratory cell and molecular biology - 1 Jan 2010
Halldorsson Skarphedinn, Gudjonsson Thorarinn, Gottfredsson Magnus, Singh Pradeep K, Gudmundsson Gudmundur Hrafn, Baldursson Olafur
Abstract excerpt
Tight junctions (TJs) play a key role in maintaining bronchial epithelial integrity, including apical-basolateral polarity and paracellular trafficking. Patients with chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) often suffer from chronic infections by the opportunistic Gr...
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