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Article

Azithromycin maintains airway epithelial integrity during Pseudomonas aeruginosa infection.

American journal of respiratory cell and molecular biology - 1 Jan 2010

Halldorsson Skarphedinn, Gudjonsson Thorarinn, Gottfredsson Magnus, Singh Pradeep K, Gudmundsson Gudmundur Hrafn, Baldursson Olafur

Abstract excerpt

Tight junctions (TJs) play a key role in maintaining bronchial epithelial integrity, including apical-basolateral polarity and paracellular trafficking. Patients with chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) often suffer from chronic infections by the opportunistic Gram-negative bacterium Pseudomonas aeruginosa, which produces multiple virulence factors, including rhamnolipids. The...

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PMID: 19372247
DOI: 10.1165/rcmb.2008-0357OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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