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Airway Epithelial Cell Junctions as Targets for Pathogens and Antimicrobial Therapy

27 Nov 2022

Abstract excerpt

Intercellular contacts between epithelial cells are established and maintained by the apical junctional complexes (AJCs). AJCs conserve cell polarity and build epithelial barriers to pathogens, inhaled allergens, and environmental particles in the respiratory tract. AJCs consist of tight junctions (TJs) and adherens junctions (AJs), which play a key role in maintaining the integrity of the airway barrier....

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PMID: 36559113
DOI: 10.3390/pharmaceutics14122619

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