Article
BRCA1 breast cancer risk is modified by CYP19 polymorphisms in Ashkenazi Jews.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2009
Raskin Leon, Lejbkowicz Flavio, Barnett-Griness Ofra, Dishon Sara, Almog Ronit, Rennert Gad
Abstract excerpt
Exposure to sex hormones is a major risk factor for breast cancer and current treatments include hormone modifying drugs, among them aromatase inhibitors. We studied the association of CYP19 (Val(80) and [TTTA](n)) polymorphisms, the gene translated to aromatase, and the risk of breast cancer in...
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