Article
Angiotensinogen T174M and M235T variants and hypertension in the Hani and Yi minority groups of China.
Biochemical genetics - 1 Jun 2009
Yuan Jiali, Tang Wenru, Chun Yinan, Ying Hua, Yang Yang, Xiao Chunjie
Abstract excerpt
A case-control study of 538 individuals investigated whether the angiotensinogen gene (AGT) might be implicated in the pathogenesis of essential hypertension in the Hani and Yi populations of China. Genotypes for two diallelic DNA polymorphisms observed at amino acid residues 174 (T174M) and 235 (M235T) within the coding sequence were determined. M235T and T174M genotyping with PCR-RFLP was performed in 267...
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