Article
AbetaPP A713T mutation in late onset Alzheimer's disease with cerebrovascular lesions.
Journal of Alzheimer's disease : JAD - 1 Jan 2009
Bernardi Livia, Geracitano Silvana, Colao Rosanna, Puccio Gianfranco, Gallo Maura, Anfossi Maria, Frangipane Francesca, Curcio Sabrina A M, Mirabelli Maria, Tomaino Carmine, Vasso Franca, Smirne Nicoletta, Maletta Raffaele, Bruni Amalia C
Abstract excerpt
Mutations in the amyloid-beta protein precursor (AbetaPP) gene can cause autosomal dominant early-onset Alzheimer's disease, or Alzheimer's disease (AD) associated with cerebral amyloid angiopathy (CAA), cerebral hemorrhage, or both. We have previously reported that the AbetaPP A713T mutation is associated with AD and subcortical ischemic lesions at magnetic resonance imaging in a large family which...
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