Article
Association between mitochondrial DNA 4,977 bp deletion and NAD(P)H:quinone oxidoreductase 1 C609T polymorphism in human breast tissues.
Oncology reports - 1 May 2009
Tseng Ling-Ming, Yin Pen-Hui, Tsai Yi-Fang, Chi Chin-Wen, Wu Chew-Wun, Lee Liang-Ming, Lee Hsin-Chen
Abstract excerpt
The NAD(P)H:quinone oxidoreductase 1 (NQO1) enzyme is implicated in protection against oxidative stress and carcinogenesis. NQO1 C609T genetic polymorphism was reported to be associated with an increased risk for cancers, including breast cancer. However, there is still lack of evidence whether h...
Topics
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- DNA, Mitochondrial
- Disease Progression
- Female
- Gene Deletion
- Genetic Predisposition to Disease
- Humans
- Middle Aged
- Molecular Sequence Data
- NAD(P)H Dehydrogenase (Quinone)
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length