Article
A dynamic network approach for the study of human phenotypes.
PLoS computational biology - 1 Apr 2009
Hidalgo César A, Blumm Nicholas, Barabási Albert-László, Christakis Nicholas A
Abstract excerpt
The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing correlations obtained from the disease history of more than 30 million patients in a Phenotypic Disease Network (PDN). We present evidence that the structure of the PDN is relevant to...
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