Article
Identification and characterization of the minimal promoter of Mipu1: the role of GC boxes in the regulation of basal transcription.
Acta biochimica et biophysica Sinica - 1 Apr 2009
Lv Ben, Tang Yiting, Li Xiayu, Wang Guiliang, Yuan Can, Liu Ying, Jiang Lei, Xiao Xianzhong
Abstract excerpt
Mipu1, a novel gene encoding a KRAB/C2H2 zinc finger protein, was first reported to be up-regulated in myocardial ischemia-reperfusion injury, functioning to protect cells against oxidative stress. To map the promoter region of the gene and to understand its regulation, we identified the transcription start site and revealed that the 1366-bp fragment upstream of the transcription start site possesses promoter...
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