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Functional role of S100A14 genetic variants and their association with esophageal squamous cell carcinoma.

Cancer research - 15 Apr 2009

Chen Hongyan, Yu Dianke, Luo Aiping, Tan Wen, Zhang Chunpeng, Zhao Dan, Yang Ming, Liu Junniao, Lin Dongxin, Liu Zhihua

Abstract excerpt

S100 proteins have been implicated in various human diseases, including certain types of cancer. Among them, S100A14 is down-regulated in esophageal squamous cell carcinoma (ESCC). In this study, we sought to identify functional genetic variants in the S100A14 locus and assessed their associations with susceptibility to ESCC. Thirty individual DNA samples were sequenced to search for genetic variations in...

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PMID: 19351828
DOI: 10.1158/0008-5472.CAN-08-4231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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