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Article

In silico Prediction of Deleterious Single Nucleotide Polymorphism in S100A4 Metastatic Gene: Potential Early Diagnostic Marker.

Contrast media & molecular imaging - 1 Jan 2022

Farhana Aisha, Kothandan Sangeetha, Alsrhani Abdullah, Mok Pooi Ling, Subbiah Suresh Kumar, Khan Yusuf Saleem

Abstract excerpt

S100A4 protein overexpression has been reported in different types of cancer and plays a key role by interacting with the tumor suppressor protein Tp53. Single nucleotide polymorphisms (SNP) in S100A4 could directly influence the biomolecular interaction with the tumor suppressor protein Tp53 due to their aberrant conformations. Hence, the study was designed to predict the deleterious SNP and its effect on the...

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Identifiers

PMID: 35965620
DOI: 10.1155/2022/4202623
PMCID: PMC9357733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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