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Article

Limits of CD133 as a marker of glioma self‐renewing cells

10 Feb 2009

Abstract excerpt

In human gliomas, self-renewing and tumor-initiating cells are characterized by the expression marker CD133. Although, widely used, the validity of CD133 is debated as recent data show that CD133(+) and CD133(-) cells share similar stemness and tumorigenic properties. To clarify this "CD133 controversy", we reexamined the methods of purification and the stem behavior of both CD133 compartments in fresh gliomas...

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PMID: 19350631
DOI: 10.1002/ijc.24352

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