Article
[Analysis on haplotypes of five HLA loci in southern Chinese Han population by sequence-based typing].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Apr 2009
Gao Su-qing, Zou Hong-yan, Cheng Liang-hong, Jing Shi-zheng, Deng Zhi-hui
Abstract excerpt
OBJECTIVE: To analyze the polymorphism and haplotypes of HLA-A, B, Cw, DRB1 and DQB1 loci in Chinese Han population. METHODS: A total of 186 unrelated healthy individuals from southern China were analyzed by sequence-based typing. Two-, three-, and five-locus haplotypes were estimated using the Expectation Maximization Algorithm. RESULTST: Twenty-eight alleles for the HLA-A locus, 49 HLA-B alleles, 24 HLA-C...
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