Article
Chromosomal deletion in patients with malignant pleural mesothelioma.
Interactive cardiovascular and thoracic surgery - 1 Jul 2009
Neragi-Miandoab Siyamek, Sugarbaker David John
Abstract excerpt
Malignant pleural mesothelioma (MPM) is associated with frequent deletions of specific chromosomal regions within 1p, 3p, 6q, 9p, 13q, 15q, and 22q. In this retrospective review of our patients with MPM, the tumor tissue of 40 patients (31 male and 9 female) was evaluated for chromosomal deletions and was karyotyped. Chromosomal deletions in regions 1p, 3p, 6p, 9p, 6q, 9q, 22q were observed in 22 of 40 patients...
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