Article
Distinct impacts of Eda and Edar loss of function on the mouse dentition.
PloS one - 1 Jan 2009
Charles Cyril, Pantalacci Sophie, Tafforeau Paul, Headon Denis, Laudet Vincent, Viriot Laurent
Abstract excerpt
BACKGROUND: The Eda-A1-Edar signaling pathway is involved in the development of organs with an ectodermal origin, including teeth. In mouse, mutants are known for both the ligand, Eda-A1 (Tabby), and the receptor, Edar (Downless). The adult dentitions of these two mutants have classically been considered to be similar. However, previous studies mentioned differences in embryonic dental development between Eda(Ta)...
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