Article
[Association of NAT2 polymorphism with risks to develop psoriasis and various dermatological diseases in Moscow population].
Molekuliarnaia biologiia - 1 Jan 2000
Kozhekbaeva Zh M, Gra O A, Fadeev V S, Goldenkova-Pavlova I V, Korsunskaia I M, Bruskin S A, Agafonova E E, Piruzian An L, Surzhikov S A, Nasedkina T V
Abstract excerpt
Ruacetyltransferase 2 (NAT2) is one of key enzymes of the second phase of biotransformation that metabolize genotoxic compounds such as carcinogens and mutagens in different types of cells. There is a correlation between the decreasing activity of NAT2 gene product and the sensitivity to harmful environmental factors that increase the risk of occurrence of different multifactorial diseases, including...
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