Article
Lymphocytic mitochondrial DNA deletions, biochemical folate status and hepatocellular carcinoma susceptibility in a case-control study.
The British journal of nutrition - 1 Sept 2009
Wu Meng-Ying, Kuo Chang-Sheng, Lin Ching-Yih, Lu Chin-Li, Syu Huang Rwei-Fen
Abstract excerpt
Mitochondrial (mt) DNA deletions and low folate status, proposed characteristics of carcinogenesis, in relation to human hepatocellular carcinoma (HCC) susceptibility are not clearly understood. We hypothesised that low folate status may modify frequencies of mtDNA deletions in humans, both of which could predispose individuals to HCC development. Biochemical folate status of serum and lymphocytes, and...
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