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Article

Genetic factors affecting drug disposition in Asian cancer patients.

Expert opinion on drug metabolism & toxicology - 1 Jan 2015

Syn Nicholas Li-Xun, Yong Wei-Peng, Lee Soo-Chin, Goh Boon-Cher

Abstract excerpt

INTRODUCTION: In the era of genomic medicine, it is increasingly recognized that ethnogeographic differences in drug pharmacology exist between Asian and other populations. This is particularly pertinent to oncology, where drugs forming the backbone of chemotherapy often have narrow therapeutic windows and are frequently dosed close to maximally tolerable levels. AREAS COVERED: At the population level, ancestry...

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Identifiers

PMID: 26548636
DOI: 10.1517/17425255.2015.1108964

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