Article
Lung carcinogenesis induced by chronic tuberculosis infection: the experimental model and genetic control.
Oncogene - 30 Apr 2009
Nalbandian A, Yan B-S, Pichugin A, Bronson R T, Kramnik I
Abstract excerpt
Coexistence of pulmonary tuberculosis (TB) and lung cancer in clinic poses significant challenges for the diagnostic and treatment of both diseases. Although association of chronic inflammation and cancer is well-documented, causal relationship between TB infection and lung cancer are not understood. We present experimental evidence that chronic TB infection induces cell dysplasia and squamous cell carcinoma...
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