Article
Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Apr 2009
de Arias Alejandro Espadas, Haworth Simone Elizabeth, Belli Luca Saverio, Burra Patrizia, Pinzello Giovambattista, Vangeli Marcello, Minola Ernesto, Guido Maria, Boccagni Patrizia, De Feo Tullia Maria, Torelli Rosanna, Cardillo Massimo, Scalamogna Mario, Poli Francesca
Abstract excerpt
In 20% to 30% of infected individuals, hepatitis C virus (HCV) can cause cirrhosis and hepatocellular carcinoma, for which liver transplantation is the best treatment available. HCV re-infection is universal, and hepatitis disease recurrence occurs in most cases with a 30% probability of progression to graft cirrhosis at 5 years post-transplant. The immunological response to HCV involves natural killer (NK) cells...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.