Article
Evolution of the NS3 and NS5B regions of the hepatitis C virus during disease recurrence after liver transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Sept 2007
Massaguer A, Ramírez S, Carrión J A, González P, Sánchez-Tapias J M, Forns X
Abstract excerpt
In patients with hepatitis C virus (HCV)-related cirrhosis, infection recurrence is universal after liver transplantation (LT). The relevance of host and virus-related factors on the outcome of hepatitis C recurrence is poorly understood. This study analyzed the relationship between the genetic evolution of the Non-Structural (NS)3 protease and NS5B polymerase regions of HCV and the severity of hepatitis C...
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