Article
The polycystic kidney disease-related proteins Bicc1 and SamCystin interact.
Biochemical and biophysical research communications - 22 May 2009
Stagner Emily E, Bouvrette Denise J, Cheng Jianlin, Bryda Elizabeth C
Abstract excerpt
Mutations in either the Bicaudal-C or the Anks6 gene which encode the Bicc1 and SamCystin proteins respectively cause formation of renal cysts in rodent models of polycystic kidney disease, however their role in the mammalian kidney is unknown. Immunolocalization studies demonstrated that, unlike many other PKD-related proteins, SamCystin and Bicc1 do not localize to the primary cilia of cultured kidney cells....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
