Article
Sequence diversity of the C-terminal region of Plasmodium falciparum merozoite surface protein 1 in southern Iran.
The Southeast Asian journal of tropical medicine and public health - 1 Jan 2009
Zamani Zahra, Razavi Mohammad Reza, Sadeghi Sedigheh, Naddaf Saeed, Pourfallah Fatemeh, Mirkhani Fatemeh, Arjmand Mohammad, Feizhaddad Hossein, Rad Mina Ebrahimi, Ebrahimi Rad Mina, Tameemi Marzieh, Assmar Mehdi
Abstract excerpt
The C-terminal region of the merozoite surface protein 1 (MSP-1) of Plasmodium falciparum is a strong vaccine candidate as it is associated with immunity to the parasite. This corresponds approximately to the conserved 17th block of the gene and is composed of two EGF- like domains. These domains exhibit only four single amino acid substitutions which show several potential variants in this region of the gene. As...
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