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Article

Mutations associated with the therapeutic efficacy of adefovir dipivoxil added to lamivudine in patients resistant to lamivudine with type B chronic hepatitis.

Journal of medical virology - 1 May 2009

Ohkawa Kazuyoshi, Takehara Tetsuo, Kato Michio, Kanada Aimi, Deguchi Matsuo, Kagita Masanori, Hikita Hayato, Sasakawa Akira, Kohga Keisuke, Uemura Akio, Sakamori Ryotaro, Yamaguchi Shinjiro, Miyagi Takuya, Ishida Hisashi, Tatsumi Tomohide, Hayashi Norio

Abstract excerpt

Factors influencing the therapeutic efficacy of adefovir dipivoxil added to continuing lamivudine have not been elucidated in lamivudine-resistant patients with type B chronic hepatitis. The viral mutations influencing the efficacy of treatment with adefovir dipivoxil were investigated by sequencing analysis of the whole virus genome. Thirty patients resistant to lamivudine receiving adefovir dipivoxil therapy...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

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Source

Identifiers

PMID: 19319954
DOI: 10.1002/jmv.21348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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