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Article

Ectopic expression of histone H2AX mutants reveals a role for its post-translational modifications.

Cancer biology & therapy - 1 Mar 2009

Rios-Doria Jonathan, Velkova Aneliya, Dapic Virna, Galán-Caridad José M, Dapic Vesna, Carvalho Marcelo A, Melendez Johana, Monteiro Alvaro N A

Abstract excerpt

Recent evidence from a wide variety of biological systems has indicated important regulatory roles for post-translation histone modifications in cellular processes such as regulation of gene expression, DNA damage response and recombination. Phosphorylation of histone H2AX at serine 139 is a critical event in the response to DNA damage, but the functional implications of this modification are not yet clear. To...

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PMID: 19305155
DOI: 10.4161/cbt.8.5.7592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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