Article
No evidence of familial correlation in breast cancer metastasis.
Breast cancer research and treatment - 1 Dec 2009
Whittemore Alice S, Stearman Beth, Venne Vickie, Halpern Jerry, Felberg Anna, McGuire Valerie, Daly Mary, Buys Saundra S
Abstract excerpt
Animal experiments support the hypothesis that the metastatic potential of breast cancer is a heritable trait of the host. Our objective was to evaluate correlations in metastasis occurrence in large families with multiple cases of breast cancer. We evaluated correlation among pairs of relatives in the occurrence and timing of distant metastasis using retrospective cohort data from 743 female breast cancer...
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