Article
Linkage and heritability analysis of migraine symptom groupings: a comparison of three different clustering methods on twin data.
Human genetics - 1 Jun 2009
Chen Carla C M, Mengersen Kerrie L, Keith Jonathan M, Martin Nicholas G, Nyholt Dale R
Abstract excerpt
Migraine is a painful disorder for which the etiology remains obscure. Diagnosis is largely based on International Headache Society criteria. However, no feature occurs in all patients who meet these criteria, and no single symptom is required for diagnosis. Consequently, this definition may not accurately reflect the phenotypic heterogeneity or genetic basis of the disorder. Such phenotypic uncertainty is...
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